Pattern Search

• PROSITE: single motifs (regexs) -best with small highly conserved sites
• eMOTIF: permissive regexs(derived from PRINTS and BLOCKS)
• Profile Library: weight matrices-good with divergent domains and superfamilies
• PRINTS: multiple motifs (fingerprints) -best for families and sub-families
• Blocks: multiple motifs (derived from InterPro and PRINTS)
• Pfam: Hidden Markov Models -good with divergent domains and superfamilies